Clinical trials (12 564)

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assignment

person_addRecruitingIPhase I

Phase 1/2 Open‑Label Study of VS‑7375, a KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and Combination Therapy in Patients with Advanced KRAS G12D‑Mutant Solid Tumors

A Coruna Galicia, Spain

Countries

Interventions

Carboplatin

Sponsors

Verastem Inc.

assignment

scheduleNot Yet RecruitingIPhase I

[18F]MC225 PET Imaging to Quantify P‑glycoprotein Function at the Blood–Brain Barrier in Patients with Suspected Glioblastoma

Groningen, The Netherlands

Countries

Interventions

[18F]Mc225

Sponsors

Universitair Medisch Centrum Groningen

assignment

scheduleNot Yet RecruitingIIIPhase III

Long-Term Safety and Efficacy of Oral Danicamtiv in Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy: Open‑Label Extension Study (KINSHIP‑OLE)

A Coruna Galicia, Spain

Countries

Interventions

Danicamtiv

Sponsors

Kardigan Inc.

assignment

scheduleNot Yet RecruitingIIIPhase III

Randomized, double‑blind, placebo‑controlled trial of SC olive pollen extract immunotherapy in patients with olive pollen‑induced allergic rhinitis ± mild asthma

Córdoba, Spain

Countries

Interventions

Allergenic Extract Of Olea Europaea Pollen Polymerized With Glutaraldehyde

Sponsors

Inmunotek S.L.

assignment

scheduleNot Yet RecruitingIPhase I

Evaluation of the Pharmacokinetic Interaction Between Brensocatib and Midazolam in Adults with Non‑Cystic Fibrosis Bronchiectasis

Groningen, The Netherlands

Countries

Sponsors

Insmed Inc.

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Double‑Blind Randomized Placebo‑Controlled Study of Oral Mitapivat on Transfusion Burden in Patients with Sickle Cell Disease

Anderlecht, Belgium

Countries

Interventions

Mitapivat

Sponsors

Agios Pharmaceuticals Inc.

assignment

person_addRecruitingIVPhase IV

Non‑inferiority of intradermal fractional dose of recombinant VZV gE/AS01B vaccine versus full‑dose intramuscular recombinant VZV gE/AS01B vaccine in adults

Leiden, The Netherlands

Countries

Interventions

Recombinant Varicella Zoster Virus Glycoprotein E

Sponsors

Leids Universitair Medisch Centrum (LUMC)

assignment

person_addRecruitingIPhase I

Phase II, randomized, placebo‑controlled trial of REM0045392 safety and efficacy in healthy elderly and Alzheimer’s disease participants

Herlev, Denmark

Countries

Sponsors

reMYND

assignment

scheduleNot Yet RecruitingIPhase I

Phase I Open‑Label Dose‑Escalation Study of Skepinone‑L Combined with Sorafenib: Safety, PK/PD and Preliminary Efficacy in Advanced Non‑Viral Hepatocellular Carcinoma

Tübingen, Germany

Countries

Sponsors

Universitaetsklinikum Tuebingen AöR

assignment

scheduleNot Yet RecruitingIPhase I

Phase I Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients with Advanced Bladder, Breast, NSCLC, and Gastric/GEJ Adenocarcinoma

Barcelona, Spain

Countries

Sponsors

Novartis Pharma AG

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Randomized Double‑Blind Trial of REGN7508 (anti‑FXI monoclonal antibody) versus Apixaban for Stroke and Systemic Embolism Prevention in Atrial Fibrillation

A Coruna Galicia, Spain

Countries

Interventions

Apixaban

Sponsors

Regeneron Pharmaceuticals Inc.

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Randomized Double‑Blind Study of REGN7508/REGN9933 for Stroke/Systemic Embolism Prevention in Atrial Fibrillation Patients Unsuitable for Oral Anticoagulation

A Coruna Galicia, Spain

Countries

Interventions

Regn7508

Sponsors

Regeneron Pharmaceuticals Inc.

assignment

scheduleNot Yet RecruitingIPhase I

Phase I/II Safety/Dose‑Finding Basket Trial of CD19‑CART01 in B‑cell–driven autoimmune diseases (SLE, SSc, DM/PM, IMNM, AAV, MG, NMOSD) and chronic GVHD

Bologna, Italy

Countries

Sponsors

Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Study of REGN7508 and REGN9933 (anti‑Factor XI antibodies) vs Placebo or Rivaroxaban in Adults post‑LE revascularization for Peripheral Artery Disease

Athens, Greece

Countries

Interventions

Regn7508

Sponsors

Regeneron Pharmaceuticals Inc.

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase III Randomized Double‑Blind Placebo‑Controlled Study of IV Trontinemab in Cognitively Unimpaired Individuals at Risk for Symptomatic Alzheimer’s Disease

Aalborg, Denmark

Countries

Interventions

Florquinitau (18F)

Sponsors

F. Hoffmann-La Roche AG

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Clinical trials (12 564)

Looking for deeper trial context?

Clinical trials (12 564)